22 Dec 2011

"BINDING SITE FREELIGHT" serum free light chain analysis

Now available PRIVATELY by Gamma Dynacare laboratories.

Provided free by OHIP  at selected Oncology clinics.

Freelite™ Serum Free Light Chain Assays

(UK) Freelite™ is a major breakthrough for the detection and monitoring of Multiple MyelomaFreelite Logo (MM) and other B-cell dyscrasia. Freelite™ assays were developed by Binding Site to measure free lambda and free kappa immunoglobulin light chains. Our expertise in the manufacture of antibodies has enabled us to provide a quantifiable, highly specific, automatable free light chain assay for serum.
Significant clinical evidence indicates the benefit of Freelite™ serum free light chain assays in initial screening for monoclonal gammopathies.  Other benefits include the identification of AL amyloidosis and Nonsecretory MM patients missed by conventional electrophoretic methods, use as a prognostic indicator for progression in myeloma, for risk stratification of MGUS patients, and rapid evaluation of treatment efficacy.
Freelite™ is a sensitive, specific marker of kappa and lambda free light chains (FLC) in serum and provides quantitative measurement of:
  • Free kappa in serum
  • Free lambda in serum
  • The serum free kappa/free lambda ratio (κ/λ)
The serum free light chain ratio is a strong indicator of monoclonality and is valuable for distinguishing monoclonal from polyclonal diseases. 

1 comment:

  1. Gamma-Dynacare Labs charge $45 for test. Gold topped tube. 1ml serum needed. Test time 5 days. (Sadly Princess Margaret Cancer Hospital does NOT use this test for follow-up of patients with Plasma cell cancer.) The test can be requested PRIVATELY by any Medical practitioner and usually paid by a personal Medical insurance.

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